Extensive perineal ecthyma gangrenosum in leukocyte adhesion deficiency type 1 associated with Staphylococcus hominis bacteremia.
Pediatr Dermatol
; 41(3): 501-503, 2024.
Article
in En
| MEDLINE
| ID: mdl-38151231
ABSTRACT
Leukocyte adhesion deficiency (LAD), a disorder of neutrophil function, is characterized by a defect in leukocyte adhesion to the endothelium. Recurrent infections in the skin, soft tissue, gingiva, and lungs due to Staphylococcus aureus, Pseudomonas aeruginosa, and Klebsiella sp. are common in these patients. Ecthyma gangrenosum (EG) is an ulcer of skin and subcutaneous tissue with a black eschar and surrounding erythematous halo secondary to a bacterial infection. Here, we report an unusual presentation of LAD type-1 with extensive EG of perineum secondary to Staphylococcus hominis bacteremia treated successfully with combination of granulocyte transfusion and diversion colostomy.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bacteremia
/
Leukocyte-Adhesion Deficiency Syndrome
/
Staphylococcus hominis
/
Ecthyma
Limits:
Female
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Pediatr Dermatol
Year:
2024
Type:
Article
Affiliation country:
India