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Meeting report of the 4th European biotransformation workshop.
Walles, M; Pähler, A; Isin, E M; Ahlqvist, Marie M.
Affiliation
  • Walles M; Pharmacokinetic Sciences, Biomedical Research, Novartis, Basel, Switzerland.
  • Pähler A; F Hoffmann-La Roche AG Research and Development Division, Pharma Research and Early Development, Basel, Switzerland.
  • Isin EM; DMPK, Translational Medicine, Paris-Saclay, France.
  • Ahlqvist MM; Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Xenobiotica ; 54(5): 257-262, 2024 May.
Article in En | MEDLINE | ID: mdl-38178690
ABSTRACT
1. Challenges, strategies and new technologies in the field of biotransformation were presented and discussed at the fourth European Biotransformation Workshop which was held in collaboration with the joint ISSX/DMDG meeting on June 15, 2023 at the University of Hertfordshire in Hatfield, UK.2. In this meeting report we summarise the presentations and discussions from this workshop.3. The topics covered are listed below Unusual biotransformation reactionsBiotransformation Workflows in Discovery utilising various softwares for structure elucidationBiotransformation software for the identification of peptide metabolitesAccelerator Mass Spectrometry (AMS) for endogenous and xenobiotic metabolite profilingMetabolite profiling using quantitative Nuclear magnetic resonance (NMR) and liquid chromatography coupled to inductively coupled plasma-mass spectrometry (LC-ICP-MS).
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biotransformation / Xenobiotics Limits: Humans Country/Region as subject: Europa Language: En Journal: Xenobiotica / Xenobiotica (Lond.) / Xenobiotica (London) Year: 2024 Type: Article Affiliation country: Switzerland

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biotransformation / Xenobiotics Limits: Humans Country/Region as subject: Europa Language: En Journal: Xenobiotica / Xenobiotica (Lond.) / Xenobiotica (London) Year: 2024 Type: Article Affiliation country: Switzerland