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Kinetic modelling of glycolytic oscillations.
van Niekerk, David D; van Wyk, Morne; Kouril, Theresa; Snoep, Jacky L.
Affiliation
  • van Niekerk DD; Department of Biochemistry, Stellenbosch University, Matieland, South Africa.
  • van Wyk M; Department of Biochemistry, Stellenbosch University, Matieland, South Africa.
  • Kouril T; Department of Biochemistry, Stellenbosch University, Matieland, South Africa.
  • Snoep JL; Department of Biochemistry, Stellenbosch University, Matieland, South Africa.
Essays Biochem ; 68(1): 15-25, 2024 Apr 30.
Article in En | MEDLINE | ID: mdl-38206647
ABSTRACT
Glycolytic oscillations have been studied for well over 60 years, but aspects of their function, and mechanisms of regulation and synchronisation remain unclear. Glycolysis is amenable to mechanistic mathematical modelling, as its components have been well characterised, and the system can be studied at many organisational levels in vitro reconstituted enzymes, cell free extracts, individual cells, and cell populations. In recent years, the emergence of individual cell analysis has opened new ways of studying this intriguing system.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycolysis / Models, Biological Limits: Animals / Humans Language: En Journal: Essays Biochem Year: 2024 Type: Article Affiliation country: South Africa
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycolysis / Models, Biological Limits: Animals / Humans Language: En Journal: Essays Biochem Year: 2024 Type: Article Affiliation country: South Africa