Mask Continuous Positive Airway Pressure Increases Diaphragm Thickening Fraction in Healthy Subjects.
Respiration
; 103(2): 100-104, 2024.
Article
in En
| MEDLINE
| ID: mdl-38228112
ABSTRACT
INTRODUCTION:
The most widespread treatment for obstructive sleep apnoea and obesity hypoventilation syndrome is continuous positive airway pressure (CPAP). The addition of inspiratory support is a potential alternative. This is a physiological study to determine the effect of CPAP and inspiratory support pressure on respiratory effort measured by diaphragm thickening fraction (DTF) in healthy volunteers.METHODS:
DTF was measured in spontaneously breathing, healthy volunteers during 4 phases (I) without connection to a ventilator, (II) on a ventilator without any applied pressures, (III) with a CPAP of 5 cmH2O, and (IV) with an additional inspiratory support pressure of 5 cmH2O.RESULTS:
Twenty-nine individuals agreed to participate. DTF was similar during the first two phases (32 ± 13% and 35 ± 22%). A considerable increase in DTF to 51 ± 21% was noted in phase III. The introduction of inspiratory support pressure during phase IV led to a reduction in DTF back to 36 ± 23% (p < 0.001). Tidal volume and minute ventilation were both slightly higher in phase IV compared to phase III.CONCLUSION:
CPAP without inspiratory support pressure increases respiratory effort measured by DTF in healthy subjects. Further research is required to investigate this phenomenon in a clinical setting.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Diaphragm
/
Continuous Positive Airway Pressure
Limits:
Humans
Language:
En
Journal:
Respiration
Year:
2024
Type:
Article
Affiliation country:
Germany