Traditional Mexican dietary pattern and cancer risk among women of Mexican descent.
Cancer Causes Control
; 35(6): 887-896, 2024 Jun.
Article
in En
| MEDLINE
| ID: mdl-38305935
ABSTRACT
PURPOSE:
To examine the association of a traditional Mexican diet score with risk of total, breast, and colorectal cancer among women of Mexican ethnic descent in the Women's Health Initiative (WHI).METHODS:
Participants were WHI enrollees who self-identified as being of Mexican descent. Data from food frequency questionnaires self-administered at study baseline were used to calculate the MexD score, with higher scores indicating greater adherence to an a priori-defined traditional Mexican diet (high in dietary fiber, vegetables, and legumes). Incident cancers were self-reported by participants from 1993 to 2020 and adjudicated by trained physicians. We used multivariable-adjusted Cox proportional hazards models to calculate hazard ratios (HRs) and 95% confidence intervals (CIs).RESULTS:
Among 2,343 Mexican descent women (median baseline age 59 years), a total of 270 cancers (88 breast, 37 colorectal) occurred during a mean follow-up of 14.4 years. The highest tertile of MexD score was associated with a lower risk of all-cancer incidence (HR 0.67; 95% CI 0.49-0.91; p-trend 0.01) and colorectal cancer (HR 0.38; 95% CI 0.14-0.998; p-trend < 0.05), with each unit increase in the MexD score associated with a 6% lower risk of all-cancer incidence (HR 0.94; 95% CI 0.88-0.99). There was no statistically significant association with risk of breast cancer.CONCLUSION:
Consumption of a traditional Mexican diet was associated with a significantly lower risk of all-cancer incidence and colorectal cancer. Confirmation of these findings in future studies is important, given the prevalence of colorectal cancer and a growing U.S. population of women of Mexican descent.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Mexican Americans
/
Diet
/
Neoplasms
Type of study:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Aged
/
Female
/
Humans
/
Middle aged
Country/Region as subject:
Mexico
Language:
En
Journal:
Cancer Causes Control
Journal subject:
EPIDEMIOLOGIA
/
NEOPLASIAS
Year:
2024
Type:
Article
Affiliation country:
United States