Accelerated elastin degradation by age-disease interaction: a common feature in age-related diseases.
NPJ Aging
; 10(1): 15, 2024 Feb 27.
Article
in En
| MEDLINE
| ID: mdl-38413600
ABSTRACT
Aging is a major driving force for many diseases but the relationship between chronological age, the aging process and age-related diseases is not fully understood. Fragmentation and loss of ultra-long-lived elastin are key features in aging and several age-related diseases leading to increased mortality. By comparing the relationship between age and elastin turnover with healthy volunteers, we show that accelerated elastin turnover by age-disease interaction is a common feature of age-related diseases.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
NPJ Aging
Year:
2024
Type:
Article
Affiliation country:
United kingdom