Contemporary report of surgical outcomes after single-stage total pancreatectomy: A 10-year experience.
J Surg Oncol
; 129(7): 1235-1244, 2024 Jun.
Article
in En
| MEDLINE
| ID: mdl-38419193
ABSTRACT
BACKGROUND:
Surgeons rarely perform elective total pancreatectomy (TP). Our study seeks to report surgical outcomes in a contemporary series of single-stage (SS) TP patients.METHODS:
Between the years 2013 to 2023 we conducted a retrospective review of 60 consecutive patients who underwent SSTP. Demographics, pathology, treatment-related variables, and survival were recorded and analyzed.RESULTS:
SSTP consisted of 3% (60/1859) of elective pancreas resections conducted. Patient median age was 68 years. Ninety percent of these patients (n = 54) underwent SSTP for pancreatic ductal adenocarcinoma (PDAC). Conversion from a planned partial pancreatectomy to TP occurred intraoperatively in 31 (52%) patients. Fifty-nine patients (98%) underwent an R0 resection. Median length of hospital stay was 6 days. The majority of morbidities were minor, with 27% patients (n = 16) developing severe complications (Clavien-Dindo ≥3). Thirty and ninety-day mortality rates were 1.67% (one patient) and 5% (three patients), respectively. Median survival for the entire cohort was 24.4 months; 22.7 months for PDAC patients, with 1-, 3-, and 5-year survival of 68%, 43%, and 16%, respectively. No mortality occurred in non-PDAC patients (n = 6).CONCLUSION:
Elective single-stage total pancreatectomy can be a safe and appropriate treatment option. SSTP should be in the armamentarium of surgeons performing pancreatic resection.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pancreatectomy
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Pancreatic Neoplasms
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Carcinoma, Pancreatic Ductal
Limits:
Adult
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Aged
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Aged80
/
Female
/
Humans
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Male
/
Middle aged
Language:
En
Journal:
J Surg Oncol
Year:
2024
Type:
Article
Affiliation country:
United States