Detection and Identification of Nitrile Compounds via Recognition-Enabled Chromatographic 19F NMR.
Anal Chem
; 96(11): 4463-4468, 2024 Mar 19.
Article
in En
| MEDLINE
| ID: mdl-38462969
ABSTRACT
The surge in applications of nitrile compounds across diverse fields, such as pharmaceuticals, agrochemicals, dyes, and functional materials, necessitates the development of rapid and efficient detection and identification methods. In this study, we introduce a chemosensing strategy employing a novel 19F-labeled probe, facilitating swift and accurate analysis of a broad spectrum of nitrile-containing analytes. This approach leverages the reversible interaction between the 19F-labeled probe and the analytes to produce chromatogram-like outputs, ensuring the precise identification of various pharmaceuticals and pesticides within complex matrices. Additionally, this dynamic system offers a versatile platform to investigate through-space 19F-19F interactions, showcasing its potential for future applications in mechanistic studies.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Anal Chem
Year:
2024
Type:
Article
Affiliation country:
China