[Neurosurgical treatment of tumors of the pineal region - literature review and overview of cases at OMIII]. / A pineális régió tumorainak idegsebészeti ellátása irodalmi áttekintés és az OMIII beteganyagának vizsgálata.
Magy Onkol
; 68(1): 27-35, 2024 Mar 14.
Article
in Hu
| MEDLINE
| ID: mdl-38484373
ABSTRACT
Pineal region tumors account for less than 1% of adult supratentorial tumors. Their treatment requires a multimodality approach. Previously, the treatment of choice was direct surgery, which is associated with high surgical risk. Advances in minimally invasive techniques and onco-radiotherapy offer a safe and multimodal personalized therapy. The aim of our study was to describe the practice of our Institute based on combined endoscopic and radiotherapy techniques. We performed a retrospective clinical study. We processed data from 23 adult patients who underwent endoscopic third ventricle fenestration and pineal tumor biopsy between 2014 and 2023. Descriptive statistics, t-test, Fisher's exact test and Kaplan-Meier analysis were performed. Clinical improvement with endoscopic intervention was achieved in 78.3% of cases. Significant increase in preoperative performance status was observed in the postoperative period (p=2.755e-5), and radiotherapy resulted in regression or stable disease. Our results suggest a safe treatment with good clinical outcome and an excellent alternative to direct surgery.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pineal Gland
/
Pinealoma
/
Brain Neoplasms
Limits:
Adult
/
Humans
Language:
Hu
Journal:
Magy Onkol
Journal subject:
NEOPLASIAS
Year:
2024
Type:
Article
Affiliation country:
Hungary