Relation of body mass index to long-term survival and cardiac remodelling for patients undergoing mitral valve replacement surgery.
Nutr Metab Cardiovasc Dis
; 34(6): 1371-1380, 2024 Jun.
Article
in En
| MEDLINE
| ID: mdl-38503618
ABSTRACT
BACKGROUND AND AIMS:
Studies have demonstrated that obesity is paradoxically associated with reduced mortality following cardiac surgery. However, these studies have treated various types of cardiac surgery as a single entity. With mitral valve (MV) surgeries being the fastest-growing cardiac surgical interventions in North America, the purpose of this study was to identify the impact of body mass index (BMI) on long-term survival and cardiac remodelling of patients undergoing MV replacement (MVR). METHODS ANDRESULTS:
In this retrospective, single-center study, 1071 adult patients who underwent an MVR between 2004 and 2018 were stratified into five BMI groups (<20, 20-24.9, 25-29.9, 30-34.9, >35). Cox proportional hazard regression models were used to determine the association between BMI and all-cause mortality. Patients who were underweight had significantly higher all-cause mortality rates at the longest follow-up (median 8.2 years) than patients with normal weight (p = 0.01). Patients who were in the obese group had significantly higher readmission rates due to myocardial infarction (MI) at the longest follow-up (p = 0.017). Subgroup analysis revealed a significant increase in long-term all-cause mortality for female patients who were underweight. Significant changes in left atrial size, mitral valve peak and mean gradients were seen in all BMI groups.CONCLUSIONS:
For patients undergoing mitral valve replacement, BMI is unrelated to operative outcomes except for patients who are underweight.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Body Mass Index
/
Heart Valve Prosthesis Implantation
/
Ventricular Remodeling
/
Mitral Valve
/
Obesity
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Nutr Metab Cardiovasc Dis
Journal subject:
ANGIOLOGIA
/
CARDIOLOGIA
/
CIENCIAS DA NUTRICAO
/
METABOLISMO
Year:
2024
Type:
Article
Affiliation country:
Canada