Immunohistochemistry-based detection of TP53 mutations in acute myeloid leukemia: a promising high sensitivity diagnostic approach.

Matthews, Andrew; Fenu, Elena; Skuli, Sarah J; Harris, Jaryse C; Bagg, Adam; Lai, Catherine

Matthews, Andrew; Fenu, Elena; Skuli, Sarah J; Harris, Jaryse C; Bagg, Adam; Lai, Catherine.

Affiliation

Matthews A; Hematology Oncology, University of Pennsylvania, Philadelphia, PA, USA.
Fenu E; Pathology, Virginia Commonwealth University Medical Center, Richmond, VA, USA.
Skuli SJ; Hematology Oncology, University of Pennsylvania, Philadelphia, PA, USA.
Harris JC; Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Bagg A; Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Lai C; Hematology Oncology, University of Pennsylvania, Philadelphia, PA, USA.

Leuk Lymphoma ; 65(7): 1012-1015, 2024 Jul.

Article in En | MEDLINE | ID: mdl-38535517

Subject(s)

Immunohistochemistry; Leukemia, Myeloid, Acute; Mutation; Tumor Suppressor Protein p53; Humans; Leukemia, Myeloid, Acute/genetics; Leukemia, Myeloid, Acute/diagnosis; Leukemia, Myeloid, Acute/pathology; Tumor Suppressor Protein p53/genetics; Sensitivity and Specificity; DNA Mutational Analysis; Biomarkers, Tumor/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunohistochemistry / Leukemia, Myeloid, Acute / Tumor Suppressor Protein p53 / Mutation Limits: Humans Language: En Journal: Leuk Lymphoma Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2024 Type: Article Affiliation country: United States

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