Triterpenoid saponins from Bupleurum marginatum and their anti-liver fibrotic activities.
J Asian Nat Prod Res
; 26(7): 858-864, 2024 Jul.
Article
in En
| MEDLINE
| ID: mdl-38572987
ABSTRACT
A new triterpenoid saponin (1), along with five known compounds (2-6), was isolated from Bupleurum marginatum Wall. ex DC, of which compounds 2-4 were obtained for the first time from this plant. The structures were confirmed by the analysis of 1D, 2D NMR, and HR-ESIMS data, and comparison with previous spectral data. Anti-liver fibrotic activities of the isolates were determined as proliferation inhibition of LPS-induced activation of HSC-T6 in vitro.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Saponins
/
Triterpenes
/
Bupleurum
Limits:
Animals
Language:
En
Journal:
J Asian Nat Prod Res
Journal subject:
BOTANICA
/
QUIMICA
Year:
2024
Type:
Article
Affiliation country:
China