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Gut microbiome is not associated with mild cognitive impairment in Parkinson's disease.
Aho, Velma T E; Klee, Matthias; Landoulsi, Zied; Heintz-Buschart, Anna; Pavelka, Lukas; Leist, Anja K; Krüger, Rejko; May, Patrick; Wilmes, Paul.
Affiliation
  • Aho VTE; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg. velma.tea.essi.aho@nmbu.no.
  • Klee M; Institute for Research on Socio-Economic Inequality (IRSEI), Department of Social Sciences, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
  • Landoulsi Z; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
  • Heintz-Buschart A; Swammerdam Institute of Life Sciences at University of Amsterdam, Amsterdam, the Netherlands.
  • Pavelka L; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
  • Leist AK; Parkinson's Research Clinic, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg.
  • Krüger R; Transversal Translational Medicine, Luxembourg Institute of Health, Strassen, Luxembourg.
  • May P; Institute for Research on Socio-Economic Inequality (IRSEI), Department of Social Sciences, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
  • Wilmes P; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
NPJ Parkinsons Dis ; 10(1): 78, 2024 Apr 06.
Article in En | MEDLINE | ID: mdl-38582855
ABSTRACT
Gut microbiome differences between people with Parkinson's disease (PD) and control subjects without Parkinsonism are widely reported, but potential alterations related to PD with mild cognitive impairment (MCI) have yet to be comprehensively explored. We compared gut microbial features of PD with MCI (n = 58) to cognitively unimpaired PD (n = 60) and control subjects (n = 90) with normal cognition. Our results did not support a specific microbiome signature related to MCI in PD.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: NPJ Parkinsons Dis Year: 2024 Type: Article Affiliation country: Luxembourg
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: NPJ Parkinsons Dis Year: 2024 Type: Article Affiliation country: Luxembourg