Quality corner: Safely using cephalosporins in almost all patients with penicillin allergies: Mini-review and suggested protocol to improve efficacy and surgical outcomes.
Gynecol Oncol Rep
; 53: 101389, 2024 Jun.
Article
in En
| MEDLINE
| ID: mdl-38623269
ABSTRACT
Surgical site infections (SSI) are one of the most common gynecologic oncology postoperative complications and they have a significant deleterious impact on the healthcare system and in patients' outcomes. Cefazolin is the recommended antibiotic in women undergoing gynecologic surgical procedures that require that require prophylaxis. However, 10-20% of patients may report a penicillin allergy which can result in administration of a less effective antibiotic. This quality review evaluated the literature around this common perioperative issue and demonstrated that healthcare teams should consider the implementation of a protocol to safely use cefazolin in most patients with a penicillin allergy. Overall, literature shows this is a safe adjustment and would improve antimicrobial stewardship, decrease SSI rates, avoid acute kidney injury, and increase cost savings.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Gynecol Oncol Rep
/
Gynecologic oncology reports
Year:
2024
Type:
Article
Affiliation country:
United States