Survival of propionic acidemia patients with liver transplant.
Mol Genet Metab Rep
; 40: 101093, 2024 Sep.
Article
in En
| MEDLINE
| ID: mdl-38846517
ABSTRACT
Propionic acidemia (PA) is a rare metabolic disorder affecting amino acid metabolism. Liver transplantation improves some outcomes, but the impact on long-term survival remains unclear. A systematic literature review and survival analysis, identifying 94 PA patients who underwent transplantation, revealed a survival probability of 62% at age 33; while median survival was estimated at 40 years. These findings highlight a substantial survival deficit of PA patients compared to the general population despite liver transplantation.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Mol Genet Metab Rep
/
Molecular genetics and metabolism reports
Year:
2024
Type:
Article
Affiliation country:
Hungary