Identification of adrenergic presynaptic and postsynaptic protein locations at neuromuscular junctions, their decrease during aging, and recovery by nicotinamide mononucleotide administration.

Takeno, Kotaro; Watanabe, Nobuhiro; Morifuji, Masashi; Hotta, Harumi; Nishimune, Hiroshi

Takeno, Kotaro; Watanabe, Nobuhiro; Morifuji, Masashi; Hotta, Harumi; Nishimune, Hiroshi.

Affiliation

Takeno K; Laboratory of Neurobiology of Aging.
Watanabe N; Department of Autonomic Neuroscience, Tokyo Metropolitan Institute for Geriatrics and Gerontology.
Morifuji M; Meiji Holdings Co., Ltd., Wellness Science Labs.
Hotta H; Department of Autonomic Neuroscience, Tokyo Metropolitan Institute for Geriatrics and Gerontology.
Nishimune H; Laboratory of Neurobiology of Aging.

Neuroreport ; 35(12): 805-812, 2024 Aug 07.

Article in En | MEDLINE | ID: mdl-38935067

Subject(s)

Aging; Neuromuscular Junction; Nicotinamide Mononucleotide; Animals; Neuromuscular Junction/drug effects; Neuromuscular Junction/metabolism; Aging/metabolism; Aging/drug effects; Mice; Nicotinamide Mononucleotide/pharmacology; Nicotinamide Mononucleotide/administration & dosage; Male; Presynaptic Terminals/metabolism; Presynaptic Terminals/drug effects; Mice, Inbred C57BL; Vesicular Monoamine Transport Proteins/metabolism; Sympathetic Nervous System/drug effects; Sympathetic Nervous System/metabolism; Receptors, Adrenergic, beta-2/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Neuromuscular Junction / Nicotinamide Mononucleotide Limits: Animals Language: En Journal: Neuroreport Journal subject: NEUROLOGIA Year: 2024 Type: Article

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