Detection and determination of active metabolites of 1-(2-o-chlorobenzoyl-4-chlorophenyl)-5-glycyl-aminomethyl-3-dimethy l-carbamoyl-1H-1,2,4-triazole hydrochloride dihydrate, (450191-S), in rat tissues, using a radioreceptor assay for benzodiazepines.

Fujimoto, M; Hashimoto, S; Takahashi, S; Hirose, K; Hatakeyama, H; Okabayashi, T

Fujimoto, M; Hashimoto, S; Takahashi, S; Hirose, K; Hatakeyama, H; Okabayashi, T.

Biochem Pharmacol ; 33(10): 1645-51, 1984 May 15.

Article in En | MEDLINE | ID: mdl-6145419

Subject(s)

Anti-Anxiety Agents/metabolism; Receptors, Cell Surface/metabolism; Triazoles/metabolism; Animals; Anti-Anxiety Agents/pharmacology; Anticonvulsants/pharmacology; Brain/drug effects; Diazepam/analysis; Hypnotics and Sedatives/pharmacology; Male; Mice; Mice, Inbred Strains; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Time Factors; Triazoles/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Anti-Anxiety Agents / Triazoles / Receptors, Cell Surface Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Biochem Pharmacol Year: 1984 Type: Article

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