Molecular localization of human class II MT2 and MT3 determinants.
J Exp Med
; 160(2): 472-93, 1984 Aug 01.
Article
in En
| MEDLINE
| ID: mdl-6206179
ABSTRACT
The specificities of the monoclonal antibodies I-LR2 and 109d6, which recognize MT2- and MT3-like serologic determinants, respectively, have been confirmed by panel testing. In addition, the relationships of these antibodies to other monoclonal antibodies and alloantisera have been studied by means of cell surface fluorescence, complement-dependent cytotoxicity and immunoprecipitation. Using these monoclonal antibodies, molecules encoded by the HLA-D region have been isolated and characterized by amino acid sequencing and peptide mapping. By these criteria, the major populations of molecules bearing MT2- and MT3-like determinants are indistinguishable from DR molecules.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Histocompatibility Testing
/
Histocompatibility Antigens Class II
/
Epitopes
Limits:
Animals
/
Female
/
Humans
/
Male
Language:
En
Journal:
J Exp Med
Year:
1984
Type:
Article