[Cytotoxic effect of methionine-gamma-lyase on neoplastic cells in culture].

Pekhov, A A; Zhukova, O S; Ivanova, T P; Zanin, V A; Dobrynin, Ia V

[Cytotoxic effect of methionine-gamma-lyase on neoplastic cells in culture]. / Tsitotoksicheskii éffekt metionin-gamma-liazy na rakovye kletki v kul'ture.

Pekhov, A A; Zhukova, O S; Ivanova, T P; Zanin, V A; Dobrynin, Ia V.

Biull Eksp Biol Med ; 95(5): 87-8, 1983 May.

Article in Ru | MEDLINE | ID: mdl-6850097

ABSTRACT

ABSTRACT

The influence of methionine-gamma-lyase from Pseudomonas putida on DNA synthesis by CaOv and L-8 cell lines has been studied. The agent has been demonstrated to inhibit the incorporation of 3H-thymidine into L-8 cell line and to have no effect on CaOv cells.

Subject(s)

Antineoplastic Agents/pharmacology; Carbon-Sulfur Lyases/pharmacology; DNA, Neoplasm/biosynthesis; Lyases/pharmacology; Animals; Cells, Cultured/drug effects; Female; L Cells/drug effects; Mice; Ovarian Neoplasms; Pseudomonas/enzymology

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Carbon-Sulfur Lyases / DNA, Neoplasm / Lyases / Antineoplastic Agents Limits: Animals Language: Ru Journal: Biull Eksp Biol Med Year: 1983 Type: Article

Search on Google

XML

PubMed Links