Antitumor activity of picolinic acid in CBA/J mice.
J Natl Cancer Inst
; 68(1): 123-6, 1982 Jan.
Article
in En
| MEDLINE
| ID: mdl-6948122
ABSTRACT
The growth of a solid tumor induced by im implantation of Ehrlich ascites tumor cells in inbred CBA/J mice was retarded by treatment with an iron chelator, picolinic acid (PLA). Survival of the mice was also significantly increased after PLA treatment. However, the iron chelator deferoxamine had no such effects; tumor growth was slightly enhanced, and survival was decreased.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Picolinic Acids
/
Carcinoma, Ehrlich Tumor
Type of study:
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
J Natl Cancer Inst
Year:
1982
Type:
Article