The suppressive effect of the catatoxic steroid, pregnenolone-16alpha-carbonitrile, on liver microsomal cholesterol-7alpha-hydroxlyase.

Mason, J I; Boyd, G S

Mason, J I; Boyd, G S.

Steroids ; 31(6): 849-54, 1978 Jun.

Article in En | MEDLINE | ID: mdl-694973

Subject(s)

Cholesterol 7-alpha-Hydroxylase/antagonists & inhibitors; Microsomes, Liver/enzymology; Pregnenolone Carbonitrile/pharmacology; Steroid Hydroxylases/antagonists & inhibitors; Animals; Cholestyramine Resin/pharmacology; Cytochrome P-450 Enzyme System/metabolism; Ethylmorphine-N-Demethylase/metabolism; Female; Male; Microsomes, Liver/drug effects; Microsomes, Liver/metabolism; Proteins/metabolism; Rats

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Collection: 01-internacional Database: MEDLINE Main subject: Pregnenolone Carbonitrile / Steroid Hydroxylases / Microsomes, Liver / Cholesterol 7-alpha-Hydroxylase Limits: Animals Language: En Journal: Steroids Year: 1978 Type: Article

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