Amniotic fluid 3,3',5'-triiodothyronine in the detection of congenital hypothyroidism.
J Clin Endocrinol Metab
; 50(4): 799-801, 1980 Apr.
Article
in En
| MEDLINE
| ID: mdl-7364933
ABSTRACT
Amniotic fluid rT3 levels were measured during pregnancy in two women who previously gave birth to infants suffering from neonatal hypothyroidism. In the first case, hypothyroidism was strongly suspected because of repeated low levels of rT3 in the amniotic fluid (20-64 ng/dl) at 16 and 31 weeks of gestation. A normal infant was delivered. He is now 10 months old and taking no treatment; he has no clinical or laboratory signs of hypothyroidism. In the second case, amniotic rT3 levels (140-180 ng/dl) were well within the normal range for 15-19 weeks of pregnancy, but an affected hypothyroid infant was born. These data suggest that amniotic fluid rT3 levels may not be a reliable tool in diagnosing intrauterine hypothyroidism.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Triiodothyronine
/
Amniotic Fluid
/
Hypothyroidism
Type of study:
Diagnostic_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Newborn
Language:
En
Journal:
J Clin Endocrinol Metab
Year:
1980
Type:
Article