A case of lymphoblastic lymphoma with aberrant morphologic feature.
Fukushima J Med Sci
; 40(2): 149-57, 1994 Dec.
Article
in En
| MEDLINE
| ID: mdl-7642166
ABSTRACT
We report a case of 33-year-old Japanese female who had B-cell lymphoblastic lymphoma with Burkitt's lymphoma (BL)-like morphologic feature. Both breasts were involved and the resected tissue showed starry sky macrophages and a proliferation of lymphoblasts containing lipid droplets. The nucleus of the lymphoblast was oval or indented. The neoplastic cells examined expressed TdT, CD10, CD14, CD38, and WH14 (a marker of pre-B cell leukemia/lymphomas). Southern blotting analysis showed a rearrangement of the immunoglobulin heavy chain gene and germline configurations of T-cell receptor gene and c-myc 3rd exon gene. The immunophenotype and genotype of this neoplasm were different from those of previously reported BLs, but identical to those of B-cell lymphoblastic lymphoma. This case, therefore, was regarded as B-cell type lymphoblastic lymphoma containing lipid droplets.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Lymphoma, B-Cell
/
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Limits:
Adult
/
Female
/
Humans
Language:
En
Journal:
Fukushima J Med Sci
Year:
1994
Type:
Article
Affiliation country:
Japan