Cystic fibrosis transmembrane conductance regulator splice variants are not conserved and fail to produce chloride channels.

Delaney, S J; Rich, D P; Thomson, S A; Hargrave, M R; Lovelock, P K; Welsh, M J; Wainwright, B J

Delaney, S J; Rich, D P; Thomson, S A; Hargrave, M R; Lovelock, P K; Welsh, M J; Wainwright, B J.

Affiliation

Delaney SJ; Centre for Molecular Biology and Biotechnology, University of Queensland, Brisbane, Australia.

Nat Genet ; 4(4): 426-31, 1993 Aug.

Article in En | MEDLINE | ID: mdl-7691356

Subject(s)

Alternative Splicing; Chloride Channels/genetics; Cystic Fibrosis/genetics; Genetic Variation; Membrane Proteins/genetics; Amino Acid Sequence; Animals; Base Sequence; Conserved Sequence; Cystic Fibrosis Transmembrane Conductance Regulator; Exons; Humans; Introns; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Organ Specificity; Polymerase Chain Reaction; Restriction Mapping

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Collection: 01-internacional Database: MEDLINE Main subject: Genetic Variation / Alternative Splicing / Chloride Channels / Cystic Fibrosis / Membrane Proteins Limits: Animals / Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 1993 Type: Article Affiliation country: Australia

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