Reversal of multidrug resistance in human colon cancer cells expressing the human MDR1 gene by liposomes in combination with monoclonal antibody or verapamil.

Sela, S; Husain, S R; Pearson, J W; Longo, D L; Rahman, A

Sela, S; Husain, S R; Pearson, J W; Longo, D L; Rahman, A.

Affiliation

Sela S; Department of Medicine, Georgetown University, Washington, D.C. 20007, USA.

J Natl Cancer Inst ; 87(2): 123-8, 1995 Jan 18.

Article in En | MEDLINE | ID: mdl-7707383

Subject(s)

Antibodies, Monoclonal/therapeutic use; Colonic Neoplasms/drug therapy; Drug Resistance, Multiple/genetics; Verapamil/therapeutic use; Vincristine/administration & dosage; ATP Binding Cassette Transporter, Subfamily B, Member 1/analysis; Colonic Neoplasms/genetics; Drug Carriers; Drug Synergism; Gene Expression; Humans; Immunoblotting; Liposomes; Time Factors; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Vincristine / Verapamil / Colonic Neoplasms / Drug Resistance, Multiple / Antibodies, Monoclonal Limits: Humans Language: En Journal: J Natl Cancer Inst Year: 1995 Type: Article Affiliation country: United States

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