Simple aromatics identified with a NFAT-lacZ transcription assay for the detection of immunosuppressants.

Burres, N S; Premachandran, U; Hoselton, S; Cwik, D; Hochlowski, J E; Ye, Q; Sunga, G N; Karwowski, J P; Jackson, M; Whittern, D N

Burres, N S; Premachandran, U; Hoselton, S; Cwik, D; Hochlowski, J E; Ye, Q; Sunga, G N; Karwowski, J P; Jackson, M; Whittern, D N.

Affiliation

Burres NS; Abbott Laboratories, Abbott Park, Illinois 60064, USA.

J Antibiot (Tokyo) ; 48(5): 380-6, 1995 May.

Article in En | MEDLINE | ID: mdl-7797439

Subject(s)

Hydroquinones/isolation & purification; Pentanols/isolation & purification; Pentanones/isolation & purification; Transcription Factors/isolation & purification; Transcription, Genetic/drug effects; Animals; Cattle; Fermentation; Gene Expression Regulation, Enzymologic; Hydroquinones/chemistry; Hydroquinones/pharmacology; Immunosuppression Therapy; Lac Operon/drug effects; Lymphocyte Activation/drug effects; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pentanols/chemistry; Pentanols/pharmacology; Pentanones/chemistry; Pentanones/pharmacology; Streptomyces; T-Lymphocytes/drug effects; Transcription Factors/chemistry; Transcription Factors/pharmacology; beta-Galactosidase/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Pentanones / Transcription Factors / Transcription, Genetic / Pentanols / Hydroquinones Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: J Antibiot (Tokyo) Year: 1995 Type: Article Affiliation country: United States

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