Preimplantation genetic diagnosis for Tay-Sachs disease: successful pregnancy after pre-embryo biopsy and gene amplification by polymerase chain reaction.

Gibbons, W E; Gitlin, S A; Lanzendorf, S E; Kaufmann, R A; Slotnick, R N; Hodgen, G D

Gibbons, W E; Gitlin, S A; Lanzendorf, S E; Kaufmann, R A; Slotnick, R N; Hodgen, G D.

Affiliation

Gibbons WE; Department of Obstetrics and Gynecology, Jones Institute of Reproductive Medicine, Eastern Virginia Medical School, Norfolk.

Fertil Steril ; 63(4): 723-8, 1995 Apr.

Article in En | MEDLINE | ID: mdl-7890054

Subject(s)

Blastocyst/pathology; Genetic Techniques; Polymerase Chain Reaction; Tay-Sachs Disease/diagnosis; Tay-Sachs Disease/genetics; Base Sequence; Biopsy; Blastomeres/pathology; Female; Fertilization in Vitro; Heterozygote; Humans; Male; Molecular Sequence Data; Oligonucleotide Probes/genetics; Pregnancy

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Collection: 01-internacional Database: MEDLINE Main subject: Tay-Sachs Disease / Blastocyst / Polymerase Chain Reaction / Genetic Techniques Type of study: Diagnostic_studies / Prognostic_studies Limits: Female / Humans / Male / Pregnancy Language: En Journal: Fertil Steril Year: 1995 Type: Article

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