Synthesis and biological properties of 5-o-carboranyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil.

Fulcrand-el Kattan, G; Goudgaon, N M; Ilksoy, N; Huang, J T; Watanabe, K A; Sommadossi, J P; Schinazi, R F

Fulcrand-el Kattan, G; Goudgaon, N M; Ilksoy, N; Huang, J T; Watanabe, K A; Sommadossi, J P; Schinazi, R F.

Affiliation

Fulcrand-el Kattan G; Veterans Affairs Medical Center (Atlanta), Decatur, Georgia 30033.

J Med Chem ; 37(16): 2583-8, 1994 Aug 05.

Article in En | MEDLINE | ID: mdl-8057301

Subject(s)

Antiviral Agents/chemical synthesis; Arabinofuranosyluracil/analogs & derivatives; Boron Compounds/chemical synthesis; Boron Neutron Capture Therapy; Radiation-Sensitizing Agents/chemical synthesis; Animals; Antiviral Agents/pharmacology; Arabinofuranosyluracil/chemical synthesis; Arabinofuranosyluracil/pharmacology; Arabinofuranosyluracil/toxicity; Bone Marrow/drug effects; Boron Compounds/pharmacology; Boron Compounds/toxicity; Cell Survival/drug effects; Female; Glioma/pathology; Glycosylation; HIV-1/drug effects; Herpesvirus 1, Human/drug effects; Humans; Lymphocytes/drug effects; Mice; Rats; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Arabinofuranosyluracil / Radiation-Sensitizing Agents / Boron Compounds / Boron Neutron Capture Therapy Limits: Animals / Female / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 1994 Type: Article

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