Induction of differentiation and growth suppression of myeloid leukemia cells by sera of patients with hematological disorders.
Anticancer Res
; 13(5C): 1905-11, 1993.
Article
in En
| MEDLINE
| ID: mdl-8267399
ABSTRACT
In severe infection, the host responds to foreign agents and produces cytokines to activate lymphocytes and macrophages. Some of these cytokines can modulate growth and differentiation of myeloid leukemia cells. We examined differentiation-inducing activities in the sera from 9 patients with leukemia or lymphoma. These results indicate that some sera from infected patients, even with acute leukemia, have significant differentiation-inducing activities on both mouse and human leukemia cells, and that cytokines having differentiation-inducing activities varied for different specimens.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Leukemia, Myeloid
/
Cytokines
Limits:
Animals
/
Humans
Language:
En
Journal:
Anticancer Res
Year:
1993
Type:
Article
Affiliation country:
Japan