Increased levels of tumor necrosis factor and interleukin 1 in bronchoalveolar lavage fluids from pigs infected with Mycoplasma hyopneumoniae.
Vet Immunol Immunopathol
; 38(3-4): 253-60, 1993 Oct.
Article
in En
| MEDLINE
| ID: mdl-8291203
ABSTRACT
We examined the levels of tumor necrosis factor (TNF)-alpha and interleukin-1 (IL-1) in bronchoalveolar lavage fluids (BALF) from pigs experimentally infected with Mycoplasma hyopneumoniae using biological assays with WEHI-164 cells and D10.G4.1 cells, respectively. Increased TNF-alpha and IL-1 in BALF were found in infected pigs with gross and/or microscopic lesions. A time-course study suggested TNF-alpha and IL-1 to be persistently elevated in infected pigs. Their presence in BALF would thus appear to be associated with the development of pneumonic lesions in M. hyopneumoniae infected pigs.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Swine Diseases
/
Bronchoalveolar Lavage Fluid
/
Interleukin-1
/
Tumor Necrosis Factor-alpha
/
Pneumonia of Swine, Mycoplasmal
Limits:
Animals
Language:
En
Journal:
Vet Immunol Immunopathol
Year:
1993
Type:
Article
Affiliation country:
Japan