Phosphorus-containing inhibitors of endothelin converting enzyme: effects of the electronic nature of phosphorus on inhibitor potency.

Bertenshaw, S R; Rogers, R S; Stern, M K; Norman, B H; Moore, W M; Jerome, G M; Branson, L M; McDonald, J F; McMahon, E G; Palomo, M A

Bertenshaw, S R; Rogers, R S; Stern, M K; Norman, B H; Moore, W M; Jerome, G M; Branson, L M; McDonald, J F; McMahon, E G; Palomo, M A.

Affiliation

Bertenshaw SR; Monsanto Corporate Research, St. Louis, Missouri 63167.

J Med Chem ; 36(1): 173-6, 1993 Jan 08.

Article in En | MEDLINE | ID: mdl-8421284

Subject(s)

Endothelins/antagonists & inhibitors; Glycopeptides/chemical synthesis; Neprilysin/antagonists & inhibitors; Organophosphorus Compounds/chemical synthesis; Animals; Chromatography, High Pressure Liquid; Glycopeptides/chemistry; Glycopeptides/pharmacology; Organophosphorus Compounds/pharmacology; Rabbits; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Organophosphorus Compounds / Glycopeptides / Neprilysin / Endothelins Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 1993 Type: Article

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