Pharmacokinetic study of a tripeptide HIV-1 protease inhibitor, KNI-174, in rats after intravenous and intraduodenal administrations.

Kiriyama, A; Mimoto, T; Kiso, Y; Takada, K

Kiriyama, A; Mimoto, T; Kiso, Y; Takada, K.

Affiliation

Kiriyama A; Department of Pharmaceutics and Pharmacokinetics, Kyoto Pharmaceutical University, Japan.

Biopharm Drug Dispos ; 14(3): 199-207, 1993 Apr.

Article in En | MEDLINE | ID: mdl-8490108

Subject(s)

Asparagine/analogs & derivatives; HIV Protease Inhibitors/pharmacokinetics; HIV-1/enzymology; Thiazoles/pharmacokinetics; Animals; Asparagine/administration & dosage; Asparagine/pharmacokinetics; Biological Availability; Chromatography, High Pressure Liquid; Duodenum; HIV Protease Inhibitors/administration & dosage; HIV-1/drug effects; Half-Life; Injections, Intravenous; Intubation, Gastrointestinal; Male; Rats; Rats, Wistar; Thiazoles/administration & dosage; Thiazolidines

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Collection: 01-internacional Database: MEDLINE Main subject: Asparagine / Thiazoles / HIV-1 / HIV Protease Inhibitors Limits: Animals Language: En Journal: Biopharm Drug Dispos Year: 1993 Type: Article Affiliation country: Japan

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