ThioTEPA pharmacokinetics during intravesical chemotherapy: the influence of dose and volume of instillate on systemic uptake and dose rate to the tumour.

Masters, J R; McDermott, B J; Harland, S; Bibby, M C; Loadman, P M

Masters, J R; McDermott, B J; Harland, S; Bibby, M C; Loadman, P M.

Affiliation

Masters JR; Institute of Urology and Nephrology, University College London, UK.

Cancer Chemother Pharmacol ; 38(1): 59-64, 1996.

Article in En | MEDLINE | ID: mdl-8603453

Subject(s)

Antineoplastic Agents, Alkylating/pharmacokinetics; Neoplasm Recurrence, Local/metabolism; Thiotepa/pharmacokinetics; Urinary Bladder Neoplasms/metabolism; Absorption; Administration, Intravesical; Aged; Analysis of Variance; Antineoplastic Agents, Alkylating/administration & dosage; Antineoplastic Agents, Alkylating/therapeutic use; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local/drug therapy; Thiotepa/administration & dosage; Thiotepa/therapeutic use; Triethylenephosphoramide/blood; Triethylenephosphoramide/urine; Urinary Bladder/metabolism; Urinary Bladder Neoplasms/drug therapy

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Collection: 01-internacional Database: MEDLINE Main subject: Urinary Bladder Neoplasms / Thiotepa / Antineoplastic Agents, Alkylating / Neoplasm Recurrence, Local Type of study: Clinical_trials Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Cancer Chemother Pharmacol Year: 1996 Type: Article Affiliation country: United kingdom

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