Correlation of altered tyrosine phosphorylation with methotrexate resistance in a cisplatin-resistant subline of L1210 cells.

Bhushan, A; Wroblewski, D; Xuan, Y; Tritton, T R; Hacker, M P

Bhushan, A; Wroblewski, D; Xuan, Y; Tritton, T R; Hacker, M P.

Affiliation

Bhushan A; Department of Pharmacology, University of Vermont College of Medicine, Burlington 05405, USA.

Biochem Pharmacol ; 51(4): 477-82, 1996 Feb 23.

Article in En | MEDLINE | ID: mdl-8619893

Subject(s)

Cisplatin/toxicity; Drug Resistance, Neoplasm; Leukemia L1210/metabolism; Membrane Proteins/metabolism; Methotrexate/toxicity; Phosphoproteins/metabolism; Phosphotyrosine/metabolism; Affinity Labels; Animals; Biological Transport, Active; Blotting, Western; Clone Cells; Electrophoresis, Polyacrylamide Gel; Membrane Proteins/isolation & purification; Methotrexate/metabolism; Mice; Molecular Weight; Phosphoproteins/isolation & purification; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Leukemia L1210 / Methotrexate / Cisplatin / Phosphotyrosine / Drug Resistance, Neoplasm / Membrane Proteins Limits: Animals Language: En Journal: Biochem Pharmacol Year: 1996 Type: Article Affiliation country: United States

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