cAMP signalling is decisive for recovery of nuclear bodies (PODs) during maturation of RA-resistant t(15;17) promyelocytic leukemia NB4 cells expressing PML-RAR alpha.

Duprez, E; Lillehaug, J R; Naoe, T; Lanotte, M

Duprez, E; Lillehaug, J R; Naoe, T; Lanotte, M.

Affiliation

Duprez E; INSERM U-301, Génétique Moléculaire et Cellulaire des Leucémies, Centre G. Hayem, Hôpital Saint-Louis, Paris, France.

Oncogene ; 12(11): 2451-9, 1996 Jun 06.

Article in En | MEDLINE | ID: mdl-8649787

Subject(s)

Cell Nucleus/drug effects; Cyclic AMP/pharmacology; Leukemia, Promyelocytic, Acute/metabolism; Neoplasm Proteins/metabolism; Nuclear Proteins; Oncogene Proteins, Fusion/metabolism; Receptors, Retinoic Acid/metabolism; Transcription Factors/metabolism; Tretinoin/pharmacology; Cell Cycle/drug effects; Cell Nucleus/metabolism; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Humans; Leukemia, Promyelocytic, Acute/genetics; Leukemia, Promyelocytic, Acute/pathology; Promyelocytic Leukemia Protein; RNA, Messenger/metabolism; Retinoic Acid Receptor alpha; Retinoid X Receptors; Translocation, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Tretinoin / Nuclear Proteins / Leukemia, Promyelocytic, Acute / Oncogene Proteins, Fusion / Cell Nucleus / Receptors, Retinoic Acid / Cyclic AMP / Neoplasm Proteins Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 1996 Type: Article Affiliation country: France

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