PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis.

Boström, H; Willetts, K; Pekny, M; Levéen, P; Lindahl, P; Hedstrand, H; Pekna, M; Hellström, M; Gebre-Medhin, S; Schalling, M; Nilsson, M; Kurland, S; Törnell, J; Heath, J K; Betsholtz, C

Boström, H; Willetts, K; Pekny, M; Levéen, P; Lindahl, P; Hedstrand, H; Pekna, M; Hellström, M; Gebre-Medhin, S; Schalling, M; Nilsson, M; Kurland, S; Törnell, J; Heath, J K; Betsholtz, C.

Affiliation

Boström H; Department of Medical Biochemistry, University of Göteborg, Sweden.

Cell ; 85(6): 863-73, 1996 Jun 14.

Article in En | MEDLINE | ID: mdl-8681381

Subject(s)

Platelet-Derived Growth Factor/physiology; Pulmonary Alveoli/growth & development; Pulmonary Emphysema/pathology; Actins/analysis; Animals; Cardiomegaly/pathology; Chimera; Crosses, Genetic; Elastin/analysis; Fibroblasts/cytology; Fibroblasts/pathology; Gene Targeting; Lung/embryology; Lung/ultrastructure; Mice; Mice, Mutant Strains; Muscle, Smooth/chemistry; Muscle, Smooth/cytology; Phenotype; Platelet-Derived Growth Factor/deficiency; Platelet-Derived Growth Factor/genetics; Pulmonary Alveoli/chemistry; Pulmonary Alveoli/cytology; Pulmonary Alveoli/pathology; RNA, Messenger/analysis; Receptor, Platelet-Derived Growth Factor alpha; Receptors, Platelet-Derived Growth Factor/analysis; Signal Transduction/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Alveoli / Pulmonary Emphysema / Platelet-Derived Growth Factor Limits: Animals Language: En Journal: Cell Year: 1996 Type: Article Affiliation country: Sweden

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