A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis.

Feder, J N; Gnirke, A; Thomas, W; Tsuchihashi, Z; Ruddy, D A; Basava, A; Dormishian, F; Domingo, R; Ellis, M C; Fullan, A; Hinton, L M; Jones, N L; Kimmel, B E; Kronmal, G S; Lauer, P; Lee, V K; Loeb, D B; Mapa, F A; McClelland, E; Meyer, N C; Mintier, G A; Moeller, N; Moore, T; Morikang, E; Prass, C E; Quintana, L; Starnes, S M; Schatzman, R C; Brunke, K J; Drayna, D T; Risch, N J; Bacon, B R; Wolff, R K

Feder, J N; Gnirke, A; Thomas, W; Tsuchihashi, Z; Ruddy, D A; Basava, A; Dormishian, F; Domingo, R; Ellis, M C; Fullan, A; Hinton, L M; Jones, N L; Kimmel, B E; Kronmal, G S; Lauer, P; Lee, V K; Loeb, D B; Mapa, F A; McClelland, E; Meyer, N C; Mintier, G A; Moeller, N; Moore, T; Morikang, E; Prass, C E; Quintana, L; Starnes, S M; Schatzman, R C; Brunke, K J; Drayna, D T; Risch, N J; Bacon, B R; Wolff, R K.

Affiliation

Feder JN; Mercator Genetics, Inc., Menlo Park, California 94025, USA.

Nat Genet ; 13(4): 399-408, 1996 Aug.

Article in En | MEDLINE | ID: mdl-8696333

Subject(s)

HLA Antigens/genetics; Hemochromatosis/genetics; Histocompatibility Antigens Class I/genetics; Membrane Proteins; Alleles; Amino Acid Sequence; Base Sequence; Biological Evolution; Chromosomes, Artificial, Yeast; Chromosomes, Human, Pair 6; Cloning, Molecular/methods; Cysteine; DNA Primers/chemistry; Gene Expression; Genes, MHC Class I; Genetic Markers; Haplotypes; Hemochromatosis Protein; Humans; Linkage Disequilibrium; Major Histocompatibility Complex; Molecular Sequence Data; RNA, Messenger/genetics; Sequence Alignment; Sequence Homology, Amino Acid

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Collection: 01-internacional Database: MEDLINE Main subject: Histocompatibility Antigens Class I / Hemochromatosis / HLA Antigens / Membrane Proteins Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 1996 Type: Article Affiliation country: United States

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