Escape mutants of HIV-1 proteinase: enzymic efficiency and susceptibility to inhibition.

Wilson, S I; Phylip, L H; Mills, J S; Gulnik, S V; Erickson, J W; Dunn, B M; Kay, J

Wilson, S I; Phylip, L H; Mills, J S; Gulnik, S V; Erickson, J W; Dunn, B M; Kay, J.

Affiliation

Wilson SI; School of Molecular and Medical Biosciences, University of Wales College of Cardiff, UK.

Biochim Biophys Acta ; 1339(1): 113-25, 1997 Apr 25.

Article in En | MEDLINE | ID: mdl-9165106

Subject(s)

Aspartic Acid Endopeptidases/genetics; HIV-1/enzymology; Anti-HIV Agents/pharmacology; Aspartic Acid Endopeptidases/antagonists & inhibitors; Aspartic Acid Endopeptidases/metabolism; Cloning, Molecular; Escherichia coli; Gene Products, gag/metabolism; HIV Protease Inhibitors/pharmacology; Mutation; Ritonavir/pharmacology; Saquinavir/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Aspartic Acid Endopeptidases / HIV-1 Language: En Journal: Biochim Biophys Acta Year: 1997 Type: Article Affiliation country: United kingdom

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