Aminoguanidine inhibits the generation of nitric oxide in vitro and prolongs islet xenograft survival in rats.

Behboo, R; Ricordi, C; Lumachi, F; Tedeschi, U; Urso, E; Cillo, U; Bonariol, L; Favia, G; D'Amico, D F

Behboo, R; Ricordi, C; Lumachi, F; Tedeschi, U; Urso, E; Cillo, U; Bonariol, L; Favia, G; D'Amico, D F.

Affiliation

Behboo R; Clinica Chirurgica I, University of Padua, Italy.

Transplant Proc ; 29(4): 2152-3, 1997 Jun.

Article in En | MEDLINE | ID: mdl-9193566

Subject(s)

Enzyme Inhibitors/pharmacology; Graft Survival/drug effects; Guanidines/pharmacology; Islets of Langerhans Transplantation/physiology; Islets of Langerhans/physiology; Nitric Oxide Synthase/biosynthesis; Nitric Oxide/metabolism; Transplantation, Heterologous/physiology; Analysis of Variance; Animals; Diabetes Mellitus, Experimental/blood; Diabetes Mellitus, Experimental/surgery; Gamma Rays; Humans; Islets of Langerhans/cytology; Islets of Langerhans/radiation effects; Male; Nitric Oxide Synthase/antagonists & inhibitors; Polymerase Chain Reaction; Rats; Rats, Wistar; Transcription, Genetic/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Transplantation, Heterologous / Islets of Langerhans Transplantation / Islets of Langerhans / Nitric Oxide Synthase / Enzyme Inhibitors / Graft Survival / Guanidines / Nitric Oxide Limits: Animals / Humans / Male Language: En Journal: Transplant Proc Year: 1997 Type: Article Affiliation country: Italy

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