Amino acid residues in both the DNA-binding and ligand-binding domains influence transcriptional activity of the human peroxisome proliferator-activated receptor alpha.

Myers, K A; Lambe, K G; Aldridge, T C; Macdonald, N; Tugwood, J D

Myers, K A; Lambe, K G; Aldridge, T C; Macdonald, N; Tugwood, J D.

Affiliation

Myers KA; Zeneca Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire, United Kingdom.

Biochem Biophys Res Commun ; 239(2): 522-6, 1997 Oct 20.

Article in En | MEDLINE | ID: mdl-9344863

Subject(s)

Amino Acids/genetics; DNA/metabolism; Microbodies/genetics; Receptors, Cytoplasmic and Nuclear/genetics; Transcription Factors/genetics; Transcription, Genetic; Alanine/genetics; Alanine/physiology; Amino Acid Substitution/genetics; Amino Acids/physiology; Humans; Ligands; Methionine/genetics; Methionine/physiology; Protein Binding/genetics; Protein Structure, Tertiary

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Transcription, Genetic / DNA / Receptors, Cytoplasmic and Nuclear / Amino Acids / Microbodies Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 1997 Type: Article Affiliation country: United kingdom

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