Study of the effective dose of a topical antifungal agent, omoconazole nitrate, on the basis of percutaneous pharmacokinetics in guinea-pigs and mice.

Hashiguchi, T; Ryu, A; Itoyama, T; Uchida, K; Yamaguchi, H

Hashiguchi, T; Ryu, A; Itoyama, T; Uchida, K; Yamaguchi, H.

Affiliation

Hashiguchi T; Tosu Research Laboratories, Hisamitsu Pharmaceutical Co., Inc, Saga, Japan.

J Pharm Pharmacol ; 49(8): 757-61, 1997 Aug.

Article in En | MEDLINE | ID: mdl-9379351

Subject(s)

Antifungal Agents/pharmacokinetics; Imidazoles/pharmacokinetics; Skin/metabolism; Administration, Topical; Animals; Antifungal Agents/administration & dosage; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Guinea Pigs; Imidazoles/administration & dosage; Mice; Mice, Hairless; Ointments; Tinea/drug therapy; Tinea/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Skin / Imidazoles / Antifungal Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Pharm Pharmacol Year: 1997 Type: Article Affiliation country: Japan

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