Brief exposure of air-filled guinea-pig isolated trachea to low levels of toluene diisocyanate (TDI) vapor in vitro increases reactivity to methacholine.

Huang, J; Frazer, D G; Millecchia, L L; Fedan, J S

Huang, J; Frazer, D G; Millecchia, L L; Fedan, J S.

Affiliation

Huang J; Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505-2845, USA.

Toxicology ; 124(2): 83-93, 1997 Dec 26.

Article in En | MEDLINE | ID: mdl-9457998

Subject(s)

Bronchoconstrictor Agents/pharmacology; Methacholine Chloride/pharmacology; Toluene 2,4-Diisocyanate/pharmacology; Trachea/drug effects; Air; Animals; Capsaicin/pharmacology; Dose-Response Relationship, Drug; Drug Interactions; Epithelium/drug effects; Guinea Pigs; In Vitro Techniques; Male; Perfusion; Specific Pathogen-Free Organisms

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Collection: 01-internacional Database: MEDLINE Main subject: Trachea / Bronchoconstrictor Agents / Methacholine Chloride / Toluene 2,4-Diisocyanate Limits: Animals Language: En Journal: Toxicology Year: 1997 Type: Article Affiliation country: United States

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