CD4+ T cell-mediated granulomatous pathology in schistosomiasis is downregulated by a B cell-dependent mechanism requiring Fc receptor signaling.

Jankovic, D; Cheever, A W; Kullberg, M C; Wynn, T A; Yap, G; Caspar, P; Lewis, F A; Clynes, R; Ravetch, J V; Sher, A

Jankovic, D; Cheever, A W; Kullberg, M C; Wynn, T A; Yap, G; Caspar, P; Lewis, F A; Clynes, R; Ravetch, J V; Sher, A.

Affiliation

Jankovic D; Immunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA. djankovic@atlas.niaid.nih.gov

J Exp Med ; 187(4): 619-29, 1998 Feb 16.

Article in En | MEDLINE | ID: mdl-9463412

Subject(s)

B-Lymphocytes/physiology; CD4-Positive T-Lymphocytes/immunology; Down-Regulation; Granuloma/pathology; Receptors, Fc/physiology; Schistosomiasis/pathology; Animals; B-Lymphocytes/immunology; Granuloma/immunology; Granuloma/parasitology; Liver/immunology; Liver/parasitology; Liver/pathology; Liver Diseases/immunology; Liver Diseases/parasitology; Liver Diseases/pathology; Mice; Mice, Inbred C57BL; Mice, Knockout; Ovum/immunology; Schistosomiasis/immunology; Signal Transduction; T-Lymphocytes, Helper-Inducer/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schistosomiasis / B-Lymphocytes / Receptors, Fc / CD4-Positive T-Lymphocytes / Down-Regulation / Granuloma Limits: Animals Language: En Journal: J Exp Med Year: 1998 Type: Article Affiliation country: United States

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