Prevention of ornithine cytotoxicity by proline in human retinal pigment epithelial cells.

Ueda, M; Masu, Y; Ando, A; Maeda, H; Del Monte, M A; Uyama, M; Ito, S

Ueda, M; Masu, Y; Ando, A; Maeda, H; Del Monte, M A; Uyama, M; Ito, S.

Affiliation

Ueda M; Department of Ophthalmology, Kansai Medical University, Osaka, Japan.

Invest Ophthalmol Vis Sci ; 39(5): 820-7, 1998 Apr.

Article in En | MEDLINE | ID: mdl-9538890

Subject(s)

Enzyme Inhibitors/pharmacology; Ornithine-Oxo-Acid Transaminase/antagonists & inhibitors; Ornithine/analogs & derivatives; Ornithine/toxicity; Pigment Epithelium of Eye/drug effects; Proline/pharmacology; Arginine/pharmacology; Carcinoma, Hepatocellular/drug therapy; Carcinoma, Hepatocellular/enzymology; Carcinoma, Hepatocellular/pathology; Cell Death/drug effects; Cell Division/drug effects; Cell Line; Cell Survival/drug effects; DNA/biosynthesis; DNA/drug effects; DNA Replication/drug effects; Dose-Response Relationship, Drug; Fibroblasts/drug effects; Fibroblasts/enzymology; Fibroblasts/pathology; Fluorescent Antibody Technique, Indirect; Humans; Keratins/metabolism; Liver Neoplasms/drug therapy; Liver Neoplasms/enzymology; Liver Neoplasms/pathology; Ornithine/metabolism; Ornithine/pharmacology; Pigment Epithelium of Eye/enzymology; Pigment Epithelium of Eye/pathology

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Collection: 01-internacional Database: MEDLINE Main subject: Ornithine / Ornithine-Oxo-Acid Transaminase / Pigment Epithelium of Eye / Proline / Enzyme Inhibitors Limits: Humans Language: En Journal: Invest Ophthalmol Vis Sci Year: 1998 Type: Article Affiliation country: Japan

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