Interferon gamma-independent rejection of interleukin 12-transduced carcinoma cells requires CD4+ T cells and Granulocyte/Macrophage colony-stimulating factor.

Zilocchi, C; Stoppacciaro, A; Chiodoni, C; Parenza, M; Terrazzini, N; Colombo, M P

Zilocchi, C; Stoppacciaro, A; Chiodoni, C; Parenza, M; Terrazzini, N; Colombo, M P.

Affiliation

Zilocchi C; Division of Experimental Oncology D, Istituto Nazionale per lo Studio e la Cura dei Tumori, 20133 Milan, Italy.

J Exp Med ; 188(1): 133-43, 1998 Jul 06.

Article in En | MEDLINE | ID: mdl-9653090

Subject(s)

CD4-Positive T-Lymphocytes/physiology; Cell Transformation, Neoplastic/genetics; Granulocyte-Macrophage Colony-Stimulating Factor/metabolism; Interferon-gamma/genetics; Interleukin-12/genetics; Animals; CD8-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/physiology; Chemokine CXCL10; Chemokines, CXC/analysis; Colonic Neoplasms/metabolism; Cytotoxicity, Immunologic/genetics; Cytotoxicity, Immunologic/immunology; Gene Expression Regulation, Neoplastic/genetics; Immunohistochemistry; In Situ Hybridization; Interleukin-12/pharmacology; Mice; Mice, Inbred BALB C; Mice, Knockout; Neoplasms, Experimental/genetics; Nitrites/metabolism; T-Lymphocytes, Cytotoxic/metabolism; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / Cell Transformation, Neoplastic / Granulocyte-Macrophage Colony-Stimulating Factor / Interferon-gamma / Interleukin-12 Limits: Animals Language: En Journal: J Exp Med Year: 1998 Type: Article Affiliation country: Italy

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