Spectrum of disorders associated with enlarged sylvian fissures in infancy.

Bingham, P M; Parrish, B; Chen, S C; Canto-Moreira, N; Zimmerman, R A

Bingham, P M; Parrish, B; Chen, S C; Canto-Moreira, N; Zimmerman, R A.

Affiliation

Bingham PM; Division of Neurology, Children's Hospital of Philadelphia, PA 19104, USA.

Neurology ; 51(6): 1732-5, 1998 Dec.

Article in En | MEDLINE | ID: mdl-9855535

ABSTRACT

ABSTRACT

Disproportionate enlargement of the sylvian fissures (ESF) on MRI of an infant's CNS suggests underdevelopment of the cortical operculum. We reviewed charts of infants with isolated ESF. Conditions associated with ESF included feeding difficulties and facial dysmorphism (syndromic or nonsyndromic). There may be an embryologic link between growth of the opercular cortex and development of the face.

Subject(s)

Cerebral Cortex/abnormalities; Developmental Disabilities/pathology; Microcephaly/pathology; Child; Child, Preschool; Developmental Disabilities/complications; Developmental Disabilities/diagnosis; Epilepsy/diagnosis; Epilepsy/pathology; Facial Bones/abnormalities; Feeding and Eating Disorders/etiology; Humans; Infant; Magnetic Resonance Imaging; Microcephaly/chemically induced; Microcephaly/complications

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Collection: 01-internacional Database: MEDLINE Main subject: Cerebral Cortex / Developmental Disabilities / Microcephaly Type of study: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limits: Child / Child, preschool / Humans / Infant Language: En Journal: Neurology Year: 1998 Type: Article Affiliation country: United States

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