CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis.

Katagiri, Y U; Sleeman, J; Fujii, H; Herrlich, P; Hotta, H; Tanaka, K; Chikuma, S; Yagita, H; Okumura, K; Murakami, M; Saiki, I; Chambers, A F; Uede, T

Katagiri, Y U; Sleeman, J; Fujii, H; Herrlich, P; Hotta, H; Tanaka, K; Chikuma, S; Yagita, H; Okumura, K; Murakami, M; Saiki, I; Chambers, A F; Uede, T.

Affiliation

Katagiri YU; Section of Immunopathogenesis, Institute of Immunological Science, Hokkaido University, Sapporo, Japan.

Cancer Res ; 59(1): 219-26, 1999 Jan 01.

Article in En | MEDLINE | ID: mdl-9892210

Subject(s)

Chemotaxis/physiology; Hyaluronan Receptors/physiology; Integrin beta1/physiology; Sialoglycoproteins/physiology; Animals; Arginine; Aspartic Acid; Binding Sites; Chemotaxis/drug effects; Glycine; Hyaluronan Receptors/chemistry; Osteopontin; Protein Binding; Rats; Sialoglycoproteins/pharmacology; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Sialoglycoproteins / Chemotaxis / Hyaluronan Receptors / Integrin beta1 Limits: Animals Language: En Journal: Cancer Res Year: 1999 Type: Article Affiliation country: Japan

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