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RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder.
Akula, N; Barb, J; Jiang, X; Wendland, J R; Choi, K H; Sen, S K; Hou, L; Chen, D T W; Laje, G; Johnson, K; Lipska, B K; Kleinman, J E; Corrada-Bravo, H; Detera-Wadleigh, S; Munson, P J; McMahon, F J.
Afiliación
  • Akula N; Human Genetics Branch, National Institute of Mental Health Intramural Research Program, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
  • Barb J; Mathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
  • Jiang X; Human Genetics Branch, National Institute of Mental Health Intramural Research Program, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
  • Wendland JR; Human Genetics Branch, National Institute of Mental Health Intramural Research Program, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
  • Choi KH; Department of Psychiatry, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
  • Sen SK; Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
  • Hou L; Human Genetics Branch, National Institute of Mental Health Intramural Research Program, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
  • Chen DT; Human Genetics Branch, National Institute of Mental Health Intramural Research Program, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
  • Laje G; Human Genetics Branch, National Institute of Mental Health Intramural Research Program, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
  • Johnson K; Bioinformatics Section, Information Technology & Bioinformatics Program, Division of Intramural Research, National Institute of Neurological Disorders & Stroke, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
  • Lipska BK; Human Brain Collection Core, Division of Intramural Research Programs, National Institute of Mental Health Intramural Research Program, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
  • Kleinman JE; Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA.
  • Corrada-Bravo H; Department of Computer Science, Institute for Advanced Computer Studies and Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, USA.
  • Detera-Wadleigh S; Human Genetics Branch, National Institute of Mental Health Intramural Research Program, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
  • Munson PJ; Mathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
  • McMahon FJ; Human Genetics Branch, National Institute of Mental Health Intramural Research Program, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
Mol Psychiatry ; 19(11): 1179-85, 2014 Nov.
Article en En | MEDLINE | ID: mdl-24393808
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trastorno Bipolar / Ritmo Circadiano / Corteza Prefrontal / Transcriptoma / GTP Fosfohidrolasas / Plasticidad Neuronal Tipo de estudio: Systematic_reviews Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trastorno Bipolar / Ritmo Circadiano / Corteza Prefrontal / Transcriptoma / GTP Fosfohidrolasas / Plasticidad Neuronal Tipo de estudio: Systematic_reviews Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos