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AKT Antagonist AZD5363 Influences Estrogen Receptor Function in Endocrine-Resistant Breast Cancer and Synergizes with Fulvestrant (ICI182780) In Vivo.
Ribas, Ricardo; Pancholi, Sunil; Guest, Stephanie K; Marangoni, Elisabetta; Gao, Qiong; Thuleau, Aurélie; Simigdala, Nikiana; Polanska, Urszula M; Campbell, Hayley; Rani, Aradhana; Liccardi, Gianmaria; Johnston, Stephen; Davies, Barry R; Dowsett, Mitch; Martin, Lesley-Ann.
Afiliación
  • Ribas R; Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, United Kingdom.
  • Pancholi S; Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, United Kingdom.
  • Guest SK; Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, United Kingdom.
  • Marangoni E; Department of Translational Research, Institut Curie, Paris, France.
  • Gao Q; Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, United Kingdom.
  • Thuleau A; Department of Translational Research, Institut Curie, Paris, France.
  • Simigdala N; Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, United Kingdom.
  • Polanska UM; Oncology Innovative Medicines, AstraZeneca, United Kingdom.
  • Campbell H; Oncology Innovative Medicines, AstraZeneca, United Kingdom.
  • Rani A; Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, United Kingdom.
  • Liccardi G; Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, United Kingdom.
  • Johnston S; Royal Marsden Hospital, London, United Kingdom.
  • Davies BR; Oncology Innovative Medicines, AstraZeneca, United Kingdom.
  • Dowsett M; Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, United Kingdom. Royal Marsden Hospital, London, United Kingdom.
  • Martin LA; Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, United Kingdom. lesley-ann.martin@icr.ac.uk.
Mol Cancer Ther ; 14(9): 2035-48, 2015 Sep.
Article en En | MEDLINE | ID: mdl-26116361

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirimidinas / Pirroles / Receptores de Estrógenos / Resistencia a Antineoplásicos / Antineoplásicos Hormonales / Inhibidores de Proteínas Quinasas / Estradiol / Proteínas Proto-Oncogénicas c-akt Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirimidinas / Pirroles / Receptores de Estrógenos / Resistencia a Antineoplásicos / Antineoplásicos Hormonales / Inhibidores de Proteínas Quinasas / Estradiol / Proteínas Proto-Oncogénicas c-akt Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido