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Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand.
den Hollander, Wouter; Boer, Cindy G; Hart, Deborah J; Yau, Michelle S; Ramos, Yolande F M; Metrustry, Sarah; Broer, Linda; Deelen, Joris; Cupples, L Adrienne; Rivadeneira, Fernando; Kloppenburg, Margreet; Peters, Marjolein; Spector, Tim D; Hofman, Albert; Slagboom, P Eline; Nelissen, Rob G H H; Uitterlinden, André G; Felson, David T; Valdes, Ana M; Meulenbelt, Ingrid; van Meurs, Joyce J B.
Afiliación
  • den Hollander W; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Boer CG; Department of Internal Medicine, Genetic Laboratory, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Hart DJ; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Yau MS; Institute for Aging Research, Hebrew SeniorLife, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
  • Ramos YFM; Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, Massachusetts, USA.
  • Metrustry S; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Broer L; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Deelen J; Department of Internal Medicine, Genetic Laboratory, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Cupples LA; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Rivadeneira F; Max Planck Institute for Biology of Ageing, Cologne, Germany.
  • Kloppenburg M; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
  • Peters M; Department of Internal Medicine, Genetic Laboratory, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Spector TD; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
  • Hofman A; Department of Internal Medicine, Genetic Laboratory, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Slagboom PE; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Nelissen RGHH; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Uitterlinden AG; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
  • Felson DT; Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Valdes AM; Department of Orthopedics, Leiden University Medical Center, Leiden, The Netherlands.
  • Meulenbelt I; Department of Internal Medicine, Genetic Laboratory, Erasmus Medical Center, Rotterdam, The Netherlands.
  • van Meurs JJB; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Ann Rheum Dis ; 76(12): 2046-2053, 2017 Dec.
Article en En | MEDLINE | ID: mdl-28855172
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteoartritis / Proteínas de Unión al Calcio / Cartílago Articular / Proteínas de la Matriz Extracelular / Predisposición Genética a la Enfermedad / Articulaciones de la Mano Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Año: 2017 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteoartritis / Proteínas de Unión al Calcio / Cartílago Articular / Proteínas de la Matriz Extracelular / Predisposición Genética a la Enfermedad / Articulaciones de la Mano Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Año: 2017 Tipo del documento: Article País de afiliación: Países Bajos